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- Penicillin protects mice against infection
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- Polio vaccine developed
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- Smallpox eradicated through vaccination
- Leprosy treatments developed
- AZT - the first drug treatment for HIV
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- Smallpox
- Spinal cord injury
- STIs - Sexually Transmitted Infections
- Stroke
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- Tuberculosis
- Whooping cough (pertussis) vaccine
- Zika
- AIDS & HIV
- Medical Procedures
- Nobel Prizes
- Serum therapy, especially in its application against diphtheria.
- Research on malaria
- The physiology of digestion
- Transmission and treatment of tuberculosis
- The structure of the nervous system
- The role played by protozoa in causing disease
- Immunity in infectious diseases
- Cell chemistry and the contents of the nucleus
- Suture of blood vessels
- Discovery of anaphylaxis
- Discoveries relating to immunity
- Capillary motor regulation
- Metabolism and the production of heat in muscles
- The discovery of insulin
- The electrocardiogram
- Discovery of the nematode Spiroptera carcinoma
- Investigations on typhus
- The importance of dietary vitamins
- Electrical activity in neurons
- The role of chromosomes in heredity
- Treatment of pernicious anaemia
- The 'organiser effect' in embryonic development
- The discovery of neurotransmitters
- Regulation of respiration
- The discovery of the antibacterial agent Prontosil
- The discovery of vitamin K
- The functions of single nerve fibres
- Production of mutations by x-rays
- The metabolism of carbohydrates
- Organisation of the brain and surgical treatment of psychosis
- Structure and function of adrenal hormones
- Yellow fever vaccine
- The citric acid cycle
- The action of oxidative enzymes
- Development of heart catheterization
- The development of drugs that block the action of biological amines
- The discovery of acquired immunological tolerance
- The mechanics of the inner ear
- The generation of action potential in nerves
- The metabolism of fatty acids and regulation of cholesterol
- Causes and treatment of tumours
- The physiology of vision
- The role of the genetic code in protein synthesis
- The storage, release and inactivation of neurotransmitters from nerve endings
- The mechanism of hormone action
- Chemical structure of antibodies
- Organisation of social behaviour patterns
- The structural and functional organisation of cells
- Interactions between tumour-viruses and genetic components of the cell
- New principles governing the behaviour, spread and causes of disease
- Hypothalamic hormones
- The CAT scan
- Identification of histocompatibility antigens and mechanism of action
- Processing of visual information by the brain
- Discovery of prostaglandins
- Techniques of monoclonal antibody formation
- Discoveries concerning the regulation of cholesterol metabolism
- Nerve growth factor and epidermal growth factor
- Discovery of genetic principle for generation of antibody diversity
- Principles for drug treatment
- Cellular origin of retroviral oncogenes
- Organ transplantation techniques
- Recording from membrane ion channels (patch clamp)
- Regulatory mechanism in cells
- Discoveries of split genes
- Discovery of G-proteins and the role of these proteins in signal transduction in cells
- Genetic control of early structural development
- Immune-system detection of virus-infected cells
- Discovery and characterisation of prions
- Nitric oxide as a signalling molecule in the cardiovascular system
- Discovery of signal peptides
- Signal transduction in the nervous system
- Regulators of the cell cycle
- Genetic regulation of development and programmed cell death
- MRI
- Odour receptors and the organisation of the olfactory system
- Discovery of H. pylori and its role in gastric and peptic ulcer disease
- RNA interference
- Knockout mice & gene targeting
- The role of HPV and HIV in causing disease
- Chromosome protection by telomeres and telomerase
- The development of in vitro fertilization
- Discoveries around innate and adaptive immunity
- Mature cells can be reprogrammed to become pluripotent
- Discoveries of machinery regulating vesicle traffic
- The discovery of penicillin
- The discovery of DDT
- The discovery of streptomycin
- Culture of the polio virus
- The inner GPS of the brain
- The replication mechanism and the genetic structure of viruses
- molecular structure of DNA
- Gene activity
- Novel therapies to treat parasitic infections
- The circadian rhythm
- Cellular autophagy
- Cancer therapy by inhibition of negative immune regulation
- The 2019 Nobel Prize: sensing and adapting to oxygen
- 2020 Nobel Prize: Discovery of Hepatitis C virus
- 2020 Nobel Prize for Chemistry: Method for genome editing
- 2021 Nobel Prize: Discovering how we feel heat and touch
- 2023 Nobel Prize: discoveries concerning nucleoside base modifications (mRNA)
- Veterinary Medicine
- African Horse Sickness
- African swine fever
- Allergies and Asthma
- Anthrax
- Bluetongue virus
- Bovine tuberculosis vaccine
- Brucellosis or Undulant fever
- Chicken cholera
- Cognitive Dysfunction Syndrome (CDS)
- Ebola vaccine & western gorillas
- Equine herpes virus
- Foot-and-mouth disease
- Identifying genetic disorders in dogs
- Microchip identification of birds
- Neutering and spaying
- Rinderpest
- Schmallenberg virus (SBV) and vaccine
- Trypanosomiasis (Sleeping sickness / nagana)
- Vaccine development
- Paget Lectures & Articles
- A scientist at work: exploring the neurobiology of sleep
- Animal research and medical progress
- Animal research for understanding animal diseases
- Animals in cancer research
- Diet and dental disease
- Is Discovery Worth The Pain?
- Is the use of animals in biomedical research still necessary? Unfortunately "yes"
- Animals and Cancer Research
- Malaria and other tropical diseases
- Manson, Ross and Reed: pioneers in research on tropical diseases
- Medical and veterinary research, with special reference to the tropics
- Nine out of ten statistics are taken out of context
- Paul Ehrlich: a hundred years of chemotherapy - 1891-1991
- Public health and experimental research
- Research and the Community
- Science and clinical myology
- The effect of research on curative medicine
- The experimental method in the conquest of disease
- The work and responsibilities of the pathologist
- The need for research on non-human primates in cognitive neuroscience
- Translating the 3Rs in complex physiological systems
- Zoonoses - diseases of animals and humans
- Some aspects of the modern conflict between sentiment and reason
- What research owes to the paget tradition
- Insulin and diabetes: the present position
- Tsetse flies and the development of Africa
- Physiological research and the vivisection act
- Research and administration - a profitable partnership
- Man as an Experimental Animal
- Humanity's Rising Debt to Medical Research
- Resistance to Infection — The Experimental Approach
- Some Reflections on Animal Experiments
- Irrationality in Public Life
- The Inevitability of Science
- The Testing of Drugs in Man
- On Taking Account of Public Opinion
- The Safety of Drugs
- The Eradication of Bovine Tuberculosis and its Importance to Man and Beast
- Mice and Men in Medical Research
- Animal Experimentation in a Large Research Institute
- Methods of Misleading Public Opinion
- Some Achievements in the Prevention of Disease
- Diabetes, Diet and Biochemistry
- The Contribution of Animal Experiments to the Surgery of Replacement
- Ethics and the Exploitation of Animals
- Alternative Methods to Animal Experiments in Medical Research
- Animals and Antigens
- Animals in Medical Progress
- Work: The Continuing Experiment in Health and Safety
- Why we need animal research
- A limited dominion
- The law of the matter, viewed in relation to its ethics
- The Swedish System of Ethical Committees in the Laboratory Animals Field
- Can Medicine Advance without Experiments on Animals?
- How animals discover drugs
- Law and the Pursuit of Knowledge
- The Science of Healthy Ageing
- Four stories about understanding the brain
- Animal Research – Then and Now
- What rodents have taught us about spatial cognition and memory
- How animals have contributed to our understanding and treatment of respiratory diseases
- 'A stroke of bad luck' by Nancy Rothwell
- Tortoise, hares, other animals on the pathway to depression
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- Simvastatin - cholesterol control
- Aspirin
- Omeprazole - stomach acid control
- Levothyroxine Sodium - thyroxine replacement
- Ramipril - for hypertension
- Amlodipine - for hypertension and angina
- Atorvastatin - cholesterol control
- Salbutamol - for asthma
- Lansoprazole - stomach acid control
- Metformin Hydrochloride - anti-diabetic
- cholecalciferol - vitamin D
- Bisoprolol fumarate - beta-blocker hypertension treatment
- Co-codamol - painkiller or analgesic
- Bendroflumethiazide - a diuretic
- Citalopram hydrobromide - an antidepressant
- Amoxicillin - an antibiotic
- Furosemide - diuretic
- Amitriptyline hydrochloride - anti-depressant
- Warfarin sodium - anticoagulant
- Paracetamol - pain relief
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- Improved Standards for Laboratory Animals Act
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- Zeitleiste
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- Diphterie durch Schutzimpfung vorgebeugt
- Entdeckung des Vitamin A
- Bluttransfusion
- Neurotransmission nachgewiesen
- Insulin isoliert
- Perniziöse Anämie
- Nutzung von Heparin als Antigerinnungsmittel
- Penicillin schützt Mäuse vor Infektionen
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- Pocken durch Impfung ausgerottet
- Entwicklung von Leprabehandlungen
- AZT - die erste medikamentöse Therapie für HIV
- Hib-meningitis vaccine
- Dolly das Schaf wird geklont
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- Erste Transplantation eines kompletten Organs mit Eigengewebe
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- Amyotrophe Lateralsklerose, ALS (Motoneuron-Krankheit)
- Anaesthetics
- Anticoagulants
- Antidepressants
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- Botulinum Toxin
- Brust Krebs
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- Cystic fibrosis
- Diabetes
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- Down-Syndrom
- Drugs for high blood pressure
- Drugs to control transplant rejection
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- HIV/AIDS Prophylaxis
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- Huntington's disease
- Influenza
- Krebs
- Leishmaniasis
- Leukämie
- Lymphom
- Malaria
- Multiple sclerosis
- Muscular dystrophy
- Prostata Krebs
- Schistosomiasis
- Schlaganfall
- Spinal cord injury
- Taubheit/Verlust des Hörvermögens
- Tuberculosis
- Whooping cough (pertussis) vaccine
- Motor neurone disease (amyotrophic lateral sclerosis)
- STIs - Sexually Transmitted Infections
- Leprosy
- Human papillomavirus (HPV)
- Smallpox
- Zika
- COVID-19 / SARS-CoV-2
- Nobelpreise
- Serum therapy, especially in its application against diphtheria.
- Research on malaria
- The physiology of digestion
- Transmission and treatment of tuberculosis
- The structure of the nervous system
- The role played by protozoa in causing disease
- Immunity in infectious diseases
- Cell chemistry and the contents of the nucleus
- Suture of blood vessels
- Discovery of anaphylaxis
- Discoveries relating to immunity
- Capillary motor regulation
- Metabolism and the production of heat in muscles
- The discovery of insulin
- The electrocardiogram
- Discovery of the nematode Spiroptera carcinoma
- Investigations on typhus
- The importance of dietary vitamins
- Electrical activity in neurons
- The role of chromosomes in heredity
- Treatment of pernicious anaemia
- The 'organiser effect' in embryonic development
- The discovery of neurotransmitters
- Regulation of respiration
- The discovery of the antibacterial agent Prontosil
- The discovery of vitamin K
- The functions of single nerve fibres
- Production of mutations by x-rays
- The metabolism of carbohydrates
- Organisation of the brain and surgical treatment of psychosis
- Structure and function of adrenal hormones
- Yellow fever vaccine
- The citric acid cycle
- The action of oxidative enzymes
- Development of heart catheterization
- The development of drugs that block the action of biological amines
- The discovery of acquired immunological tolerance
- The mechanics of the inner ear
- Die Entstehung des Aktionspotentials in Nervenzellen
- The metabolism of fatty acids and regulation of cholesterol
- Causes and treatment of tumours
- Die Physiologe des Sehens
- Die Rolle des genetischen Codes bei der Proteinsynthese
- The storage, release and inactivation of neurotransmitters from nerve endings
- The mechanism of hormone action
- Chemical structure of antibodies
- Organisation of social behaviour patterns
- The structural and functional organisation of cells
- Interactions between tumour-viruses and genetic components of the cell
- New principles governing the behaviour, spread and causes of disease
- Hypothalamic hormones
- The CAT scan
- Identification of histocompatibility antigens and mechanism of action
- Processing of visual information by the brain
- Discovery of prostaglandins
- Techniques of monoclonal antibody formation
- Discoveries concerning the regulation of cholesterol metabolism
- Nerve growth factor and epidermal growth factor
- Discovery of genetic principle for generation of antibody diversity
- Principles for drug treatment
- Cellular origin of retroviral oncogenes
- Organ transplantation techniques
- Recording from membrane ion channels (patch clamp)
- Regulatory mechanism in cells
- Discoveries of split genes
- Discovery of G-proteins and the role of these proteins in signal transduction in cells
- Genetic control of early structural development
- Immune-system detection of virus-infected cells
- Discovery and characterisation of prions
- Nitric oxide as a signalling molecule in the cardiovascular system
- Discovery of signal peptides
- Signal transduction in the nervous system
- Regulators of the cell cycle
- Genetic regulation of development and programmed cell death
- MRI
- Odour receptors and the organisation of the olfactory system
- Discovery of H. pylori and its role in gastric and peptic ulcer disease
- RNA interference
- Knockout mice & gene targeting
- The role of HPV and HIV in causing disease
- Chromosome protection by telomeres and telomerase
- The development of in vitro fertilization
- Discoveries around innate and adaptive immunity
- Mature cells can be reprogrammed to become pluripotent
- Discoveries of machinery regulating vesicle traffic
- The discovery of penicillin
- The discovery of DDT
- The discovery of streptomycin
- Culture of the polio virus
- The inner GPS of the brain
- The replication mechanism and the genetic structure of viruses
- Gene activity
- Novel therapies to treat parasitic infections
- molecular structure of DNA
- Die innere Uhr
- Cellular autophagy
- Cancer therapy by inhibition of negative immune regulation
- Veterinärmedizin
- Ebola-Impfstoff & westliche Gorillas
- Herpesvirusinfektion des Pferdes
- Identifizierung von Erbkrankheiten bei Hunden
- Impfstoff gegen Rindertuberkulose
- Impfstoffentwicklung
- Mikrochip-Kennzeichnung von Vögeln
- Rinderpest
- Trypanosomiasis (Schlafkrankheit / Nagana-Seuche)
- Chicken cholera
- Anthrax
- Foot-and-mouth disease
- African swine fever
- African Horse Sickness
- Artikel und Vorlesungen
- A scientist at work: exploring the neurobiology of sleep
- Animal research and medical progress
- Animal research for understanding animal diseases
- Animals in cancer research
- Diet and dental disease
- Is Discovery Worth The Pain?
- Is the use of animals in biomedical research still necessary? Unfortunately "yes"
- Animals and Cancer Research
- Malaria and other tropical diseases
- Manson, Ross and Reed: pioneers in research on tropical diseases
- Medical and veterinary research, with special reference to the tropics
- Nine out of ten statistics are taken out of context
- Paul Ehrlich: a hundred years of chemotherapy - 1891-1991
- Public health and experimental research
- Research and the Community
- Science and clinical myology
- The effect of research on curative medicine
- The experimental method in the conquest of disease
- The work and responsibilities of the pathologist
- The need for research on non-human primates in cognitive neuroscience
- Translating the 3Rs in complex physiological systems
- Zoonoses - diseases of animals and humans
- Some aspects of the modern conflict between sentiment and reason
- What research owes to the paget tradition
- Insulin and diabetes: the present position
- Tsetse flies and the development of Africa
- Physiological research and the vivisection act
- Research and administration - a profitable partnership
- Man as an Experimental Animal
- Humanity's Rising Debt to Medical Research
- Resistance to Infection — The Experimental Approach
- Some Reflections on Animal Experiments
- Irrationality in Public Life
- The Inevitability of Science
- The Testing of Drugs in Man
- On Taking Account of Public Opinion
- The Safety of Drugs
- The Eradication of Bovine Tuberculosis and its Importance to Man and Beast
- Animal Experimentation in a Large Research Institute
- Methods of Misleading Public Opinion
- Some Achievements in the Prevention of Disease
- Diabetes, Diet and Biochemistry
- The Contribution of Animal Experiments to the Surgery of Replacement
- Mice and Men in Medical Research
- Four stories about understanding the brain
- Research in the news
- Medical Procedures
- Zeitleiste
- Arzneimittelentwicklung
- Der Prozess
- Sicherheit und Tests
- Modernisierung des Prozesses
- Top 20 prescribed medicines
- Simvastatin - Cholesterinsenker
- Aspirin
- Omeprazol - zur Kontrolle von Magensäure
- Levothyroxin-Natrium – ein Ersatzstoff für Thyroxin
- Ramipril – gegen Hypertonie
- Amlodipin – gegen Bluthochdruck und Angina
- Paracetamol - Schmerzmittel
- Atorvastatin - Cholesterinsenker
- Salbutamol – gegen Asthma
- Lansoprazol – zur Kontrolle von Magensäure
- Metforminhydrochlorid - Antidiabetikum
- cholecalciferol - vitamin D
- Bisoprolol fumarate – Betablocker zur Behandlung von Bluthochdruck
- Co-codamol (Codeine/Acetaminophen) – Schmerzmittel oder Analgetikum
- Bendroflumethiazid - ein Diuretikum
- Citalopram hydrobromide – ein Antidepressivum
- Amoxicillin – ein Antibiotikum
- Fursosemid - Diuretikum
- Amitriptylin (Hydrochlorid) – Antidepressivum
- Warfarin Sodium - Antikoagulans (Gerinnungshemmer)
- Antibiotics
- Ressourcen
- Fragen & Antworten
- Zitate
- "...a basis for looking to the future, both in terms of where primates may continue to be necessary and where alternatives may replace their use"
- "...animal research is essential to tackling major 21st century health problems such as cancer and heart disease. Without the use of animals it would be impossible, in many cases, to develop drugs or any sort of medical treatment."
- "...carefully controlled and planned animal experiments have made a vital contribution to the discovery and utility of the well-known classes of antibiotics"
- "...if it comes to a choice between regulated studies on a few animals and a treatment for an incurable disease... most people reluctantly make the same choice."
- "...It is a legal requirement to carry out animal testing to ensure they are safe and effective"
- "...the discovery and development of these and the other major anti-asthmatic drugs would not have been possible without animal research
- "...the few experiments we carry out on primates have the potential to alleviate a vast amount of human suffering"
- "...to continue to be one of the world centres for scientific research, we have to stand up and be counted in support of researchers, go on marches and demonstrations, and back even tougher action by the police and the courts against these terrorists."
- "...we must support and protect individuals and companies engaged in life saving medical research"
- "...with the current scientific knowledge, not enough alternative methods are yet available to replace the use of non-human primates"
- "An absolute position that all animal experiments are scientifically invalid is untenable"
- "Animal experimentation has been essential to the development of all cardiac surgery, transplantation surgery, joint replacements and all vaccinations."
- "Animal experiments have been vital to the discovery and development of many advances in physiology and medicine"
- "Animal research and testing has played a part in almost every medical breakthrough of the last century. It has saved hundreds of millions of lives worldwide..."
- "Animal research has lead to advances in the treatment of many conditions... Where there is no alternative available, we will continue to ensure that the balance between animal welfare and scientific advancement is maintained."
- "Animal research saves lives, but wherever possible alternatives should be used,"
- "As science rapidly develops it is important that the case for using non-human primates in biomedical research is continually evaluated."
- "Biomedial science has not yet reached the stage where there are adequate replacements for the use of non-human primates in research"
- "certain animal models have played significant roles in the study of particular diseases"
- "Current proposals to restrict non-human primate research in the EU could prevent... work which could have outcomes of immense benefit to human health."
- "Double standards...make ethical debate difficult..."
- "everybody has benefited immensely from scientific research involving animals"
- "experiments on animals have contributed greatly to scientific advances"
- "genetically normal and GM animals [have] contributed significantly to biomedical understanding
- "I abhor vivisection. It should at least be curbed. Better, it should be abolished. I know of no achievement through vivisection, no scientific discovery, that could not have been obtained without such barbarism and cruelty. The whole thing is evil.
- "I believe that if we really wanted to, we could work steadily towards a day in 10 to 20 years time when animal experimentation will have disappeared."
- "It is hard to imagine how brain prosthetics and brain-machine interfaces, which are tantalizingly close to realization, could be properly developed without the support of fundamental primate studies."
- "It would be perverse to deny that curative treatments and diagnostic advances owe their emergence to animal experiments"
- "On the basis of probability theory we would have been better off tossing a coin."
- "Our work is not driven by the pleasure of harming an animal..."
- "Primate models are only used when animals such as rats and mice cannot be used"
- "Producing a new medicine is a lengthy and complex process... Tests on animals play a vital role"
- "Research on animals has contributed to almost every medical advance of the last century."
- "Research using animals has made an important contribution to advances in medicine and surgery...
- "Research using animals is essential to produce sufficient evidence efficacy and safety before proceeding to trials involving humans"
- "Research using non-human primates has played a major role in improving human and animal health, and this continues to be the case"
- "Studies using non-human primates are undertaken alongside other animal models and observational and intervational research using humans and in vitro approaches."
- "The finding demonstrates how critically important studies in monkeys are to the understanding of HIV infection...Current proposals to restrict non-human primate research in the EU could prevent this type of work..."
- "The idea, as I understand it, is that fundamental truths are revealed in laboratory experiments on lower animals and are then applied to the problems of the sick patient... It is plain nonsense."
- "The recent discovery of highly specific antidepressants and anti-anxiety medications would not have been possible without the use of animal models"
- "The use of animals in medical research and safety testing is a vital part of the quest to improve human health."
- "the work on [polio] prevention was long delayed by... misleading experimental models of the disease in monkeys"
- "There are some answers which are very difficult to do on anything other than a primate"
- "There is no way that the heart-lung machine could have been devised and developed other than through studies on living creatures"
- "There needs to be clearer communication for the public avout how valuable it [animal testing] is.
- "until suitable alternatives are found, this vital work should continue so that hundreds of millions more lives can be saved in the future"
- "We remain of the view that in many areas of research we are still reliant on primates to achieve our goals for improving human health"
- "With primate research able to make real contibutions to alleciating devastating conditions like Parkinson's disease and HIV/AIDS, the harmful consequences that could result from abandoning this work are clear"
- "Without animal testing, there will be no new drugs for new or hard-to-treat diseases..."
- "[A primate ban] would force us to abandon research that could lead to treatments for Alzheimer's, motor neurone disease, strokes and many other illnesses"
- "[knockout mice] truly provided a revolution in mammalian biology,
- "[monkeys] are used only when no other species and no alternatice approach can provide the answers to questions about such conditions as Alzhemers, stroke, Parkinson's, spinal injury, hormone disorders, and vaccines for HIV"
- 'Although rare, the use of primates in medical research and testing is invaluable, as an essential aspect of work wihch provides the best hope for breakthroughs in important areas..."
- 'Animal tests...less predicitve than tossing a coin.'
- 'Animals are only used where deemed absolutely necessary and their use is rigorously regulated by UK legislation which is the toughest in the world. '
- 'Green Party policy is to phase out all animal testing...'
- 'I support [FRAME's] objectives, largely because I do not believe that results of tests conducted on animals will be neccessarily relevant to human beings...'
- 'I was very much afraid. Before this, we had been doing this work only on pigs.'
- 'properly controlled medical research involving animals... will prove relavent to increasing knowledge of human health in the future"
- 'The animal testing regime... is utterly futile'
- 'The use of animals in medical research remains absolutely essential....'
- 'We are concerned by the upward trend in the use of animals in scientific procedures...'
- 'We are proud of our standards, we are proud of the way we go about our experiments and the fact that the animals do not suffer in almost all situations....'
- Unabhängige Experten
- House of Lords Select Committee on Animals in Scientific Procedures
- Identifying the enviromental causes of disease:
- In vivo sciences in the UK: sustaining the supply of skills in the 21st century
- Investigation into the Home Office regulation of animal experimentation
- Investigations into adverse incidents during clinical trials of TGN1412
- Memorandum for House of Lords Select Committee on Animals in Scientific Procedures
- Review of cost-benefit assessment in the use of animals in research
- Study into the use of non-human primates (NHP) in research - (Weatherall report)
- The Duff Report
- The Ethics of Research Involving Animals
- The use of animals in vaccine testing for humans
- The use of genetically modified animals
- Toxicity Testing in the 21st Century: A Vision and a Strategy (Brief Summary)
- UK Stem Cell Initiative
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- Research and administration - a profitable partnership
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- "...a basis for looking to the future, both in terms of where primates may continue to be necessary and where alternatives may replace their use"
- "...animal research is essential to tackling major 21st century health problems such as cancer and heart disease. Without the use of animals it would be impossible, in many cases, to develop drugs or any sort of medical treatment."
- "...carefully controlled and planned animal experiments have made a vital contribution to the discovery and utility of the well-known classes of antibiotics"
- "...if it comes to a choice between regulated studies on a few animals and a treatment for an incurable disease... most people reluctantly make the same choice."
- "...It is a legal requirement to carry out animal testing to ensure they are safe and effective"
- "...the discovery and development of these and the other major anti-asthmatic drugs would not have been possible without animal research
- "...the few experiments we carry out on primates have the potential to alleviate a vast amount of human suffering"
- "...to continue to be one of the world centres for scientific research, we have to stand up and be counted in support of researchers, go on marches and demonstrations, and back even tougher action by the police and the courts against these terrorists."
- "...we must support and protect individuals and companies engaged in life saving medical research"
- "...with the current scientific knowledge, not enough alternative methods are yet available to replace the use of non-human primates"
- "An absolute position that all animal experiments are scientifically invalid is untenable"
- "Animal experimentation has been essential to the development of all cardiac surgery, transplantation surgery, joint replacements and all vaccinations."
- "Animal experiments have been vital to the discovery and development of many advances in physiology and medicine"
- "Animal research and testing has played a part in almost every medical breakthrough of the last century. It has saved hundreds of millions of lives worldwide..."
- "Animal research has lead to advances in the treatment of many conditions... Where there is no alternative available, we will continue to ensure that the balance between animal welfare and scientific advancement is maintained."
- "Animal research saves lives, but wherever possible alternatives should be used,"
- "As science rapidly develops it is important that the case for using non-human primates in biomedical research is continually evaluated."
- "Biomedial science has not yet reached the stage where there are adequate replacements for the use of non-human primates in research"
- "certain animal models have played significant roles in the study of particular diseases"
- "Current proposals to restrict non-human primate research in the EU could prevent... work which could have outcomes of immense benefit to human health."
- "Double standards...make ethical debate difficult..."
- "everybody has benefited immensely from scientific research involving animals"
- "experiments on animals have contributed greatly to scientific advances"
- "genetically normal and GM animals [have] contributed significantly to biomedical understanding
- "I abhor vivisection. It should at least be curbed. Better, it should be abolished. I know of no achievement through vivisection, no scientific discovery, that could not have been obtained without such barbarism and cruelty. The whole thing is evil.
- "I believe that if we really wanted to, we could work steadily towards a day in 10 to 20 years time when animal experimentation will have disappeared."
- "It is hard to imagine how brain prosthetics and brain-machine interfaces, which are tantalizingly close to realization, could be properly developed without the support of fundamental primate studies."
- "It would be perverse to deny that curative treatments and diagnostic advances owe their emergence to animal experiments"
- "On the basis of probability theory we would have been better off tossing a coin."
- "Our work is not driven by the pleasure of harming an animal..."
- "Primate models are only used when animals such as rats and mice cannot be used"
- "Producing a new medicine is a lengthy and complex process... Tests on animals play a vital role"
- "Research on animals has contributed to almost every medical advance of the last century."
- "Research using animals has made an important contribution to advances in medicine and surgery...
- "Research using animals is essential to produce sufficient evidence efficacy and safety before proceeding to trials involving humans"
- "Research using non-human primates has played a major role in improving human and animal health, and this continues to be the case"
- "Studies using non-human primates are undertaken alongside other animal models and observational and intervational research using humans and in vitro approaches."
- "The finding demonstrates how critically important studies in monkeys are to the understanding of HIV infection...Current proposals to restrict non-human primate research in the EU could prevent this type of work..."
- "The idea, as I understand it, is that fundamental truths are revealed in laboratory experiments on lower animals and are then applied to the problems of the sick patient... It is plain nonsense."
- "The recent discovery of highly specific antidepressants and anti-anxiety medications would not have been possible without the use of animal models"
- "The use of animals in medical research and safety testing is a vital part of the quest to improve human health."
- "the work on [polio] prevention was long delayed by... misleading experimental models of the disease in monkeys"
- "There are some answers which are very difficult to do on anything other than a primate"
- "There is no way that the heart-lung machine could have been devised and developed other than through studies on living creatures"
- "There needs to be clearer communication for the public avout how valuable it [animal testing] is.
- "until suitable alternatives are found, this vital work should continue so that hundreds of millions more lives can be saved in the future"
- "We remain of the view that in many areas of research we are still reliant on primates to achieve our goals for improving human health"
- "With primate research able to make real contibutions to alleciating devastating conditions like Parkinson's disease and HIV/AIDS, the harmful consequences that could result from abandoning this work are clear"
- "Without animal testing, there will be no new drugs for new or hard-to-treat diseases..."
- "[A primate ban] would force us to abandon research that could lead to treatments for Alzheimer's, motor neurone disease, strokes and many other illnesses"
- "[knockout mice] truly provided a revolution in mammalian biology,
- "[monkeys] are used only when no other species and no alternatice approach can provide the answers to questions about such conditions as Alzhemers, stroke, Parkinson's, spinal injury, hormone disorders, and vaccines for HIV"
- 'Although rare, the use of primates in medical research and testing is invaluable, as an essential aspect of work wihch provides the best hope for breakthroughs in important areas..."
- 'Animal tests...less predicitve than tossing a coin.'
- 'Animals are only used where deemed absolutely necessary and their use is rigorously regulated by UK legislation which is the toughest in the world. '
- 'Green Party policy is to phase out all animal testing...'
- 'I support [FRAME's] objectives, largely because I do not believe that results of tests conducted on animals will be neccessarily relevant to human beings...'
- 'I was very much afraid. Before this, we had been doing this work only on pigs.'
- 'properly controlled medical research involving animals... will prove relavent to increasing knowledge of human health in the future"
- 'The animal testing regime... is utterly futile'
- 'The use of animals in medical research remains absolutely essential....'
- 'We are concerned by the upward trend in the use of animals in scientific procedures...'
- 'We are proud of our standards, we are proud of the way we go about our experiments and the fact that the animals do not suffer in almost all situations....'
- Inchieste di esperti indipendenti
- House of Lords Select Committee on Animals in Scientific Procedures
- Identifying the enviromental causes of disease:
- In vivo sciences in the UK: sustaining the supply of skills in the 21st century
- Investigation into the Home Office regulation of animal experimentation
- Investigations into adverse incidents during clinical trials of TGN1412
- Memorandum for House of Lords Select Committee on Animals in Scientific Procedures
- Review of cost-benefit assessment in the use of animals in research
- Study into the use of non-human primates (NHP) in research - (Weatherall report)
- The Duff Report
- The Ethics of Research Involving Animals
- The use of animals in vaccine testing for humans
- The use of genetically modified animals
- Toxicity Testing in the 21st Century: A Vision and a Strategy (Brief Summary)
- UK Stem Cell Initiative
- Raccolta di recensioni
- Biografie
- Organismi di ricerca
- 3M
- Abbott Laboratories Ltd
- Academy of Medical Royal Colleges
- Action Medical Research
- Allergan
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- Alzheimers Research Trust
- Amersham Place
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- Animal Procedures Committee
- Aptuit (Edinburgh) Ltd
- Association for the Study of Animal Behaviour
- Association of Medical Research Charities
- Association of the British Pharmaceutical Industry
- Astellas Pharma
- Asthma UK
- Aston University Birmingham
- AstraZeneca
- Babraham Institute
- Baxter
- Bayer
- BioIndustry Association
- Biomedical Research Education Trust
- Biosciences Federation
- Biotechnology and Biological Sciences Council ( BBSRC)
- Boyd Group
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- Breast Cancer Campaign (BCC)
- Bristol-Myers Squibb
- British Association for Psychopharmacology
- British Heart Foundation
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- Centre for Ecology & Hydrology
- Charles River Laboratorie
- City University
- Coalition for Medical Progress
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- Merck, Sharp and Dohme
- Migraine Trust
- Motor Neurone Disease Association
- Multiple Sclerosis Society
- Muscular Dystrophy Campaign
- National Centre for the 3Rs
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- New principles governing the behaviour, spread and causes of disease
- Hypothalamic hormones
- The CAT scan
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- Processing of visual information by the brain
- Discovery of prostaglandins
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- Nitric oxide as a signalling molecule in the cardiovascular system
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- MRI
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- Discovery of H. pylori and its role in gastric and peptic ulcer disease
- RNA interference
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- The role of HPV and HIV in causing disease
- Chromosome protection by telomeres and telomerase
- The development of in vitro fertilization
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- The discovery of penicillin
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- molecular structure of DNA
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- Autofagia celular
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- Medicina veterinaria
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- Artículos y charlas
- A scientist at work: exploring the neurobiology of sleep
- Animal research and medical progress
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- Is Discovery Worth The Pain?
- Is the use of animals in biomedical research still necessary? Unfortunately "yes"
- Animals and Cancer Research
- Malaria and other tropical diseases
- Manson, Ross and Reed: pioneers in research on tropical diseases
- Medical and veterinary research, with special reference to the tropics
- Nine out of ten statistics are taken out of context
- Paul Ehrlich: a hundred years of chemotherapy - 1891-1991
- Public health and experimental research
- Research and the Community
- Science and clinical myology
- The effect of research on curative medicine
- The experimental method in the conquest of disease
- The work and responsibilities of the pathologist
- The need for research on non-human primates in cognitive neuroscience
- Translating the 3Rs in complex physiological systems
- Zoonoses - diseases of animals and humans
- Physiological research and the vivisection act
- Tsetse flies and the development of Africa
- Insulin and diabetes: the present position
- What research owes to the paget tradition
- Some aspects of the modern conflict between sentiment and reason
- Research and administration - a profitable partnership
- Man as an Experimental Animal
- Humanity's Rising Debt to Medical Research
- Resistance to Infection — The Experimental Approach
- Some Reflections on Animal Experiments
- Irrationality in Public Life
- The Inevitability of Science
- The Testing of Drugs in Man
- On Taking Account of Public Opinion
- The Safety of Drugs
- The Eradication of Bovine Tuberculosis and its Importance to Man and Beast
- Mice and Men in Medical Research
- Animal Experimentation in a Large Research Institute
- Methods of Misleading Public Opinion
- Some Achievements in the Prevention of Disease
- Diabetes, Diet and Biochemistry
- The Contribution of Animal Experiments to the Surgery of Replacement
- Four stories about understanding the brain
- Research in the news
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- Línea de tiempo
- Desarrollo Farmacológico
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- Los 20 medicamentos más recetados
- Simvastatina - para controlar el colesterol
- Aspirina
- Omeprazol - para la acidez de estómago
- Lexotiroxina sódica - para reemplazar la tiroxina
- Ramipril - para la hipertensión
- Amlodipina - para la hipertensión y la angina
- Paracetamol - para aliviar el dolor
- Atorvastatina - para controlar el colesterol
- Salbutamol - para el asma
- Lansoprazol - para controlar el ácido del estómago
- Hidrocloruro de metformina - un antidiabético
- Colecalciferol - una vitamina D
- Bisoprolol fumarato - un betabloqueador para el tratamiento de la hipertensión
- Co-codamol - para aliviar el dolor o analgésico
- Bendroflumetiazida - un medicamento diurético
- Citalopram hidrobromuro - un antidepresivo
- La amoxicilina - un antibiótico
- La furosemida - un diurético
- La amitriptilina hidrocloruro - contra la depresión
- Warfarina sódica - un anticoagulante
- Fármaco originados de venenos
- Antibiotics
- Recursos
- Preguntas frecuentes
- Base de datos de citas
- "...a basis for looking to the future, both in terms of where primates may continue to be necessary and where alternatives may replace their use"
- "...animal research is essential to tackling major 21st century health problems such as cancer and heart disease. Without the use of animals it would be impossible, in many cases, to develop drugs or any sort of medical treatment."
- "...carefully controlled and planned animal experiments have made a vital contribution to the discovery and utility of the well-known classes of antibiotics"
- "...if it comes to a choice between regulated studies on a few animals and a treatment for an incurable disease... most people reluctantly make the same choice."
- "...It is a legal requirement to carry out animal testing to ensure they are safe and effective"
- "...the discovery and development of these and the other major anti-asthmatic drugs would not have been possible without animal research
- "...the few experiments we carry out on primates have the potential to alleviate a vast amount of human suffering"
- "...to continue to be one of the world centres for scientific research, we have to stand up and be counted in support of researchers, go on marches and demonstrations, and back even tougher action by the police and the courts against these terrorists."
- "...we must support and protect individuals and companies engaged in life saving medical research"
- "...with the current scientific knowledge, not enough alternative methods are yet available to replace the use of non-human primates"
- "An absolute position that all animal experiments are scientifically invalid is untenable"
- "Animal experimentation has been essential to the development of all cardiac surgery, transplantation surgery, joint replacements and all vaccinations."
- "Animal experiments have been vital to the discovery and development of many advances in physiology and medicine"
- "Animal research and testing has played a part in almost every medical breakthrough of the last century. It has saved hundreds of millions of lives worldwide..."
- "Animal research has lead to advances in the treatment of many conditions... Where there is no alternative available, we will continue to ensure that the balance between animal welfare and scientific advancement is maintained."
- "Animal research saves lives, but wherever possible alternatives should be used,"
- "As science rapidly develops it is important that the case for using non-human primates in biomedical research is continually evaluated."
- "Biomedial science has not yet reached the stage where there are adequate replacements for the use of non-human primates in research"
- "certain animal models have played significant roles in the study of particular diseases"
- "Current proposals to restrict non-human primate research in the EU could prevent... work which could have outcomes of immense benefit to human health."
- "Double standards...make ethical debate difficult..."
- "everybody has benefited immensely from scientific research involving animals"
- "experiments on animals have contributed greatly to scientific advances"
- "genetically normal and GM animals [have] contributed significantly to biomedical understanding
- "I abhor vivisection. It should at least be curbed. Better, it should be abolished. I know of no achievement through vivisection, no scientific discovery, that could not have been obtained without such barbarism and cruelty. The whole thing is evil.
- "I believe that if we really wanted to, we could work steadily towards a day in 10 to 20 years time when animal experimentation will have disappeared."
- "It is hard to imagine how brain prosthetics and brain-machine interfaces, which are tantalizingly close to realization, could be properly developed without the support of fundamental primate studies."
- "It would be perverse to deny that curative treatments and diagnostic advances owe their emergence to animal experiments"
- "On the basis of probability theory we would have been better off tossing a coin."
- "Our work is not driven by the pleasure of harming an animal..."
- "Primate models are only used when animals such as rats and mice cannot be used"
- "Producing a new medicine is a lengthy and complex process... Tests on animals play a vital role"
- "Research on animals has contributed to almost every medical advance of the last century."
- "Research using animals has made an important contribution to advances in medicine and surgery...
- "Research using animals is essential to produce sufficient evidence efficacy and safety before proceeding to trials involving humans"
- "Research using non-human primates has played a major role in improving human and animal health, and this continues to be the case"
- "Studies using non-human primates are undertaken alongside other animal models and observational and intervational research using humans and in vitro approaches."
- "The finding demonstrates how critically important studies in monkeys are to the understanding of HIV infection...Current proposals to restrict non-human primate research in the EU could prevent this type of work..."
- "The idea, as I understand it, is that fundamental truths are revealed in laboratory experiments on lower animals and are then applied to the problems of the sick patient... It is plain nonsense."
- "The recent discovery of highly specific antidepressants and anti-anxiety medications would not have been possible without the use of animal models"
- "The use of animals in medical research and safety testing is a vital part of the quest to improve human health."
- "the work on [polio] prevention was long delayed by... misleading experimental models of the disease in monkeys"
- "There are some answers which are very difficult to do on anything other than a primate"
- "There is no way that the heart-lung machine could have been devised and developed other than through studies on living creatures"
- "There needs to be clearer communication for the public avout how valuable it [animal testing] is.
- "until suitable alternatives are found, this vital work should continue so that hundreds of millions more lives can be saved in the future"
- "We remain of the view that in many areas of research we are still reliant on primates to achieve our goals for improving human health"
- "With primate research able to make real contibutions to alleciating devastating conditions like Parkinson's disease and HIV/AIDS, the harmful consequences that could result from abandoning this work are clear"
- "Without animal testing, there will be no new drugs for new or hard-to-treat diseases..."
- "[A primate ban] would force us to abandon research that could lead to treatments for Alzheimer's, motor neurone disease, strokes and many other illnesses"
- "[knockout mice] truly provided a revolution in mammalian biology,
- "[monkeys] are used only when no other species and no alternatice approach can provide the answers to questions about such conditions as Alzhemers, stroke, Parkinson's, spinal injury, hormone disorders, and vaccines for HIV"
- 'Although rare, the use of primates in medical research and testing is invaluable, as an essential aspect of work wihch provides the best hope for breakthroughs in important areas..."
- 'Animal tests...less predicitve than tossing a coin.'
- 'Animals are only used where deemed absolutely necessary and their use is rigorously regulated by UK legislation which is the toughest in the world. '
- 'Green Party policy is to phase out all animal testing...'
- 'I support [FRAME's] objectives, largely because I do not believe that results of tests conducted on animals will be neccessarily relevant to human beings...'
- 'I was very much afraid. Before this, we had been doing this work only on pigs.'
- 'properly controlled medical research involving animals... will prove relavent to increasing knowledge of human health in the future"
- 'The animal testing regime... is utterly futile'
- 'The use of animals in medical research remains absolutely essential....'
- 'We are concerned by the upward trend in the use of animals in scientific procedures...'
- 'We are proud of our standards, we are proud of the way we go about our experiments and the fact that the animals do not suffer in almost all situations....'
- Consultas a especialistas independientes
- House of Lords Select Committee on Animals in Scientific Procedures
- Identifying the enviromental causes of disease:
- In vivo sciences in the UK: sustaining the supply of skills in the 21st century
- Investigation into the Home Office regulation of animal experimentation
- Investigations into adverse incidents during clinical trials of TGN1412
- Memorandum for House of Lords Select Committee on Animals in Scientific Procedures
- Review of cost-benefit assessment in the use of animals in research
- Study into the use of non-human primates (NHP) in research - (Weatherall report)
- The Duff Report
- The Ethics of Research Involving Animals
- The use of animals in vaccine testing for humans
- The use of genetically modified animals
- Toxicity Testing in the 21st Century: A Vision and a Strategy (Brief Summary)
- UK Stem Cell Initiative
- Reseñas bibliográficas
- Biografías
- Organizaciones de investigación
- 3M
- Abbott Laboratories Ltd
- Academy of Medical Royal Colleges
- Action Medical Research
- Allergan
- Alzheimer's Society
- Alzheimers Research Trust
- Amersham Place
- Amicus
- Animal Procedures Committee
- Aptuit (Edinburgh) Ltd
- Association for the Study of Animal Behaviour
- Association of Medical Research Charities
- Association of the British Pharmaceutical Industry
- Astellas Pharma
- Asthma UK
- Aston University Birmingham
- AstraZeneca
- Babraham Institute
- Baxter
- Bayer
- BioIndustry Association
- Biomedical Research Education Trust
- Biosciences Federation
- Biotechnology and Biological Sciences Council ( BBSRC)
- Boyd Group
- Breakthrough Breast Cancer
- Breast Cancer Campaign (BCC)
- Bristol-Myers Squibb
- British Association for Psychopharmacology
- British Heart Foundation
- British Medical Association
- British Neuroscience Association
- British Pharmacological Society
- British Psychological Society
- British Society for Animal Science
- British Society for Immunology
- British Veterinary Association
- Cancer Research UK
- Centre for Ecology & Hydrology
- Charles River Laboratorie
- City University
- Coalition for Medical Progress
- Council for International Organizations of Medical Sciences (CIOMS)
- Council of Heads of Medical Schools
- Covance
- De Montfort University
- Deafness Research UK (aka The Hearing Research Trust)
- DebRA UK
- Defra
- Department of Health
- Diabetes UK
- DuPont
- EFPIA (The European Federation of Pharmaceutical Industries and Associations)
- Farm Animal Welfare Council
- GE Healthcare
- Glasgow Caledonian University
- GlaxoSmithKline (GSK)
- Harlan
- Heart Research UK
- Help the Aged
- Home Office
- Huntingdon Life Sciences (HLS)
- Imperial College London
- Institute of Animal Technology
- Institute of Food Research (IFR)
- Institute of Grassland and Environmental Research (IGER)
- International Council for Laboratory Animal Science (ICLAS)
- IVTIP
- Jeans for Gens
- Johnson & Johnson
- Juvenile Diabetes Research Foundation
- Kidney Research UK
- King's College London
- Laboratory Animal Veterinary Association
- Laboratory Animals Breeders Association of Great Britain
- Laboratory Animals Science Association
- Lundbeck
- Medical Mouse
- Medical Research Council
- Meningitis Research Foundation
- Merck, Sharp and Dohme
- Migraine Trust
- Motor Neurone Disease Association
- Multiple Sclerosis Society
- Muscular Dystrophy Campaign
- National Centre for the 3Rs
- National Institute for Biological Standards and Control (NIBSC)
- National Institute for Medical Research
- National Osteoporosis Society
- Novartis
- Novo Nordisk
- Nuffield Council on Bioethics
- Open University
- Parkinson's Disease Society
- Patients' Voice for Medical Advance
- Pfizer
- Physiological Society
- Pro-Test
- Proctor & Gamble
- Queen Mary College, University of London
- Queen's University Belfast
- Reckitt Benckiser plc
- Roche
- Roslin Institute (RI)
- Royal Society
- Sanofi-Aventis
- Science Media Centre
- Sense about Science
- Sequani
- Sheffield Hallam University
- SHERT, Scottish Hospital Endowments Research Trust
- Shire plc
- Society for Endocrinology
- Society for Experimental Biology
- Society of Toxicology
- St George's Hospital Medical School
- Stand up for Science
- Syngenta
- The Academy of Medical Sciences
- The People's Petition
- The PSP Association
- The University of Birmingham
- UCL
- Understanding Animal Research
- Universities Federation for Animal Welfare
- University House
- University Loughborough
- University of Aberdeen
- University of Bath
- University of Belfast
- University of Bristol
- University of Cambridge
- University of Cardiff
- University of Derby
- University of Dundee
- University of Edinburgh
- University of Glamorgan
- University of Glasgow
- University of Leeds
- University of Leicester
- University of Liverpool
- University of Manchester
- University of Newcastle upon Tyne
- University of Oxford
- University of Roehampton
- University of Salford
- University of Sheffield
- University of Southampton
- University of St Andrews
- University of Strathclyde
- University of Wales, Aberystwyth
- University of Warwick
- University of York
- Univesity of Nottingham
- Veterinary Laboratories Agency
- Wellcome Trust
- World Medical Association
- Eli Lilly and Company
- Genzyme
- The Stroke Association
- Reglamentación y legislación
- EU Directive on the protection of animals used for scientific purposes
- Animal Enterprise Protection Act
- Animal Welfare Act
- Animal Welfare Act - New Zealand
- Animal Welfare Act amendments 1970
- Animal Welfare Act amendments 1976
- Animals (Scientific Procedures) Act
- Australian code of practice for the care and use of animals for scientific purposes
- Code of Federal Regulations - Animal Welfare
- EU council directive 76/768/EEC
- EU directive 86/609/EEC
- European Chemicals Regulation (REACH) 1907/2006/EC
- Improved Standards for Laboratory Animals Act
- ETS 123
- Enlaces
- French
- À propos de nous
- Concevoir la recherche
- Pourquoi utiliser des animaux
- Animaux de recherche
- C. elegans (ver nématode)
- Le chat
- La poule
- Les crustacés Decapoda
- Le chien
- Drosophila melanogaster
- Ferret
- Fish (other)
- L'amphibien
- GM mouse
- Le cochon d'Inde
- Minipig
- La souris
- La souris génétiquement modifiée (GM)
- La souris (immunodéficiente)
- L'hétérocéphale
- Autres mammifères
- Other or unspecified invertebrates
- Les autres rongeurs
- Les primates
- La caille
- Le lapin
- Le rat
- Le rat (GM)
- Les reptiles
- Le mouton
- Le calmar
- Le poisson-zèbre
- Pufferfish
- Sea Urchin
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- Kangaroo
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- Bee
- Armadillo
- Conception et analyse de l’expérimentation
- Chemical Toxicology
- Alternatives et les 3R
- Idées fausses
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- Chronologie
- La théorie microbienne
- La découverte du cycle de vie du parasite du paludisme
- Les souris et la génétique
- La première intervention chirurgicale de transplantation sur un être humain
- L'immunisation empêche la diphtérie
- La découverte de la vitamine A
- La transfusion sanguine
- La démonstration de la neurotransmission
- L'isolation de l'insuline
- L'anémie pernicieuse
- L'utilisation de l'héparine comme anticoagulant
- La pénicilline protège les souris de l'infection
- Le développement de la dialyse pour l'insuffisance rénale
- Le développement d'un vaccin contre la poliomyélite
- Les stimulateurs cardiaques
- Les valves cardiaques artificielles
- La réussite des greffes cardiaques sur l'homme
- L'éradication de la variole par la vaccination
- Le développement de traitements de la lèpre
- L'AZT - le premier traitement du VIH
- Le vaccin contre la méningite à Hib
- Le clonage de la brebis Dolly
- Le séquençage et l'analyse d'un génome de souris
- La première transplantation d'un organe issu de l'ingénierie tissulaire
- Maladies et recherche
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- La surdité ou perte auditive
- Le diabète
- Drugs for high blood pressure
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- Hepatitis B
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- Le cancer du sein
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- Le SIDA et le VIH
- L'hépatite C
- HIV/AIDS Prophylaxis
- Huntington's disease
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- Prix Nobel
- Serum therapy, especially in its application against diphtheria.
- Research on malaria
- The physiology of digestion
- Transmission and treatment of tuberculosis
- The structure of the nervous system
- The role played by protozoa in causing disease
- Immunity in infectious diseases
- Cell chemistry and the contents of the nucleus
- Suture of blood vessels
- Discovery of anaphylaxis
- Discoveries relating to immunity
- Capillary motor regulation
- Metabolism and the production of heat in muscles
- The discovery of insulin
- The electrocardiogram
- Discovery of the nematode Spiroptera carcinoma
- Investigations on typhus
- The importance of dietary vitamins
- Electrical activity in neurons
- The role of chromosomes in heredity
- Treatment of pernicious anaemia
- The 'organiser effect' in embryonic development
- The discovery of neurotransmitters
- Regulation of respiration
- The discovery of the antibacterial agent Prontosil
- The discovery of vitamin K
- The functions of single nerve fibres
- Production of mutations by x-rays
- The metabolism of carbohydrates
- Organisation of the brain and surgical treatment of psychosis
- Structure and function of adrenal hormones
- Yellow fever vaccine
- The citric acid cycle
- The action of oxidative enzymes
- Development of heart catheterization
- The development of drugs that block the action of biological amines
- The discovery of acquired immunological tolerance
- The mechanics of the inner ear
- The generation of action potential in nerves
- The metabolism of fatty acids and regulation of cholesterol
- Causes and treatment of tumours
- La physiologie de la vision
- Le rôle du code génétique dans la synthèse protéique.
- Le stockage, la libération et l’inactivation des neurotransmetteurs dans les terminaisons nerveuses
- Les mécanismes de l’activité hormonale
- Chemical structure of antibodies
- Organisation of social behaviour patterns
- The structural and functional organisation of cells
- Interactions between tumour-viruses and genetic components of the cell
- New principles governing the behaviour, spread and causes of disease
- Hypothalamic hormones
- The CAT scan
- Identification of histocompatibility antigens and mechanism of action
- Processing of visual information by the brain
- Discovery of prostaglandins
- Techniques of monoclonal antibody formation
- Discoveries concerning the regulation of cholesterol metabolism
- Nerve growth factor and epidermal growth factor
- Discovery of genetic principle for generation of antibody diversity
- Principles for drug treatment
- Cellular origin of retroviral oncogenes
- Organ transplantation techniques
- Recording from membrane ion channels (patch clamp)
- Regulatory mechanism in cells
- La découverte de l’épissage génétique
- Discovery of G-proteins and the role of these proteins in signal transduction in cells
- Genetic control of early structural development
- Immune-system detection of virus-infected cells
- Discovery and characterisation of prions
- Nitric oxide as a signalling molecule in the cardiovascular system
- Discovery of signal peptides
- Signal transduction in the nervous system
- Regulators of the cell cycle
- Genetic regulation of development and programmed cell death
- MRI
- Odour receptors and the organisation of the olfactory system
- Discovery of H. pylori and its role in gastric and peptic ulcer disease
- RNA interference
- Knockout mice & gene targeting
- The role of HPV and HIV in causing disease
- Chromosome protection by telomeres and telomerase
- The development of in vitro fertilization
- Discoveries around innate and adaptive immunity
- Mature cells can be reprogrammed to become pluripotent
- Discoveries of machinery regulating vesicle traffic
- The discovery of penicillin
- The discovery of DDT
- The discovery of streptomycin
- Culture of the polio virus
- Le GPS biologique du cerveau
- Nouvelles thérapies pour traiter les infections parasitaires
- Gene activity
- molecular structure of DNA
- The replication mechanism and the genetic structure of viruses
- Autophagie cellulaire
- Le rythme circadien
- Cancer therapy by inhibition of negative immune regulation
- Médecine vétérinaire
- Le vaccin contre la tuberculose bovine
- Le virus de l'herpès équin
- L'identification des oiseaux par micropuce
- L'identification des troubles génétiques chez les chiens
- La trypanosomiase (Maladie du sommeil/Nagana)
- Le développement de vaccin
- Le vaccin contre le virus Ebola et les gorilles de l'Ouest
- La peste bovine
- Anthrax
- Chicken cholera
- Foot-and-mouth disease
- African swine fever
- African Horse Sickness
- Articles et Conférences
- A scientist at work: exploring the neurobiology of sleep
- Animal research and medical progress
- Animal research for understanding animal diseases
- Animals in cancer research
- Diet and dental disease
- Is Discovery Worth The Pain?
- Is the use of animals in biomedical research still necessary? Unfortunately "yes"
- Animals and Cancer Research
- Malaria and other tropical diseases
- Manson, Ross and Reed: pioneers in research on tropical diseases
- Medical and veterinary research, with special reference to the tropics
- Nine out of ten statistics are taken out of context
- Paul Ehrlich: a hundred years of chemotherapy - 1891-1991
- Public health and experimental research
- Research and the Community
- Science and clinical myology
- The effect of research on curative medicine
- The experimental method in the conquest of disease
- The work and responsibilities of the pathologist
- The need for research on non-human primates in cognitive neuroscience
- Translating the 3Rs in complex physiological systems
- Zoonoses - diseases of animals and humans
- Some aspects of the modern conflict between sentiment and reason
- Insulin and diabetes: the present position
- Tsetse flies and the development of Africa
- Physiological research and the vivisection act
- What research owes to the paget tradition
- Irrationality in Public Life
- Some Reflections on Animal Experiments
- Resistance to Infection — The Experimental Approach
- Humanity's Rising Debt to Medical Research
- Man as an Experimental Animal
- Research and administration - a profitable partnership
- The Contribution of Animal Experiments to the Surgery of Replacement
- Diabetes, Diet and Biochemistry
- Some Achievements in the Prevention of Disease
- Methods of Misleading Public Opinion
- Animal Experimentation in a Large Research Institute
- Mice and Men in Medical Research
- The Eradication of Bovine Tuberculosis and its Importance to Man and Beast
- The Safety of Drugs
- On Taking Account of Public Opinion
- The Testing of Drugs in Man
- The Inevitability of Science
- Four stories about understanding the brain
- Research in the news
- Medical Procedures
- Chronologie
- Mise au point de médicaments
- Le processus
- Sécurité et essais
- Moderniser le procédé
- Top 20 prescribed medicines
- Simvastatine – le contrôle du cholestérol
- Aspirine
- Oméprazole – contrôle de l’acide gastrique
- Lévothyroxine Sodium - remplacement de thyroxine
- Ramipril – contre l’hypertension
- Amlodipine – contre l’hypertension et l’angine
- Paracetamol – analgésique
- Atorvastatine – contrôle du cholestérol
- Salbutamol – contre l’asthme
- Lansoprazole – Contrôle de l’acide gastrique
- Chlorhydrate de metformine – antidiabétique
- Cholécalciférol – vitamine D
- Fumarate de bisoprolol – traitement bêtabloqueur contre l’hypertension
- Co-codamol – analgésique ou antalgique
- Bendrofluméthiazide – un diurétique
- Citalopram hydrobromide - an antidepressantBromhydrate de citalopram – un antidépresseur
- Amoxicilline – un antibiotique
- Furosémide – un diurétique
- Chlorhydrate d’Amitriptyline – un antidépresseur
- Warfarine sodique – un anticoagulant
- Médicaments à base de venins
- Antibiotics
- Ressources
- FAQ
- Base de données de citations
- "...a basis for looking to the future, both in terms of where primates may continue to be necessary and where alternatives may replace their use"
- "...animal research is essential to tackling major 21st century health problems such as cancer and heart disease. Without the use of animals it would be impossible, in many cases, to develop drugs or any sort of medical treatment."
- "...carefully controlled and planned animal experiments have made a vital contribution to the discovery and utility of the well-known classes of antibiotics"
- "...if it comes to a choice between regulated studies on a few animals and a treatment for an incurable disease... most people reluctantly make the same choice."
- "...It is a legal requirement to carry out animal testing to ensure they are safe and effective"
- "...the discovery and development of these and the other major anti-asthmatic drugs would not have been possible without animal research
- "...the few experiments we carry out on primates have the potential to alleviate a vast amount of human suffering"
- "...to continue to be one of the world centres for scientific research, we have to stand up and be counted in support of researchers, go on marches and demonstrations, and back even tougher action by the police and the courts against these terrorists."
- "...we must support and protect individuals and companies engaged in life saving medical research"
- "...with the current scientific knowledge, not enough alternative methods are yet available to replace the use of non-human primates"
- "An absolute position that all animal experiments are scientifically invalid is untenable"
- "Animal experimentation has been essential to the development of all cardiac surgery, transplantation surgery, joint replacements and all vaccinations."
- "Animal experiments have been vital to the discovery and development of many advances in physiology and medicine"
- "Animal research and testing has played a part in almost every medical breakthrough of the last century. It has saved hundreds of millions of lives worldwide..."
- "Animal research has lead to advances in the treatment of many conditions... Where there is no alternative available, we will continue to ensure that the balance between animal welfare and scientific advancement is maintained."
- "Animal research saves lives, but wherever possible alternatives should be used,"
- "As science rapidly develops it is important that the case for using non-human primates in biomedical research is continually evaluated."
- "Biomedial science has not yet reached the stage where there are adequate replacements for the use of non-human primates in research"
- "certain animal models have played significant roles in the study of particular diseases"
- "Current proposals to restrict non-human primate research in the EU could prevent... work which could have outcomes of immense benefit to human health."
- "Double standards...make ethical debate difficult..."
- "everybody has benefited immensely from scientific research involving animals"
- "experiments on animals have contributed greatly to scientific advances"
- "genetically normal and GM animals [have] contributed significantly to biomedical understanding
- "I abhor vivisection. It should at least be curbed. Better, it should be abolished. I know of no achievement through vivisection, no scientific discovery, that could not have been obtained without such barbarism and cruelty. The whole thing is evil.
- "I believe that if we really wanted to, we could work steadily towards a day in 10 to 20 years time when animal experimentation will have disappeared."
- "It is hard to imagine how brain prosthetics and brain-machine interfaces, which are tantalizingly close to realization, could be properly developed without the support of fundamental primate studies."
- "It would be perverse to deny that curative treatments and diagnostic advances owe their emergence to animal experiments"
- "On the basis of probability theory we would have been better off tossing a coin."
- "Our work is not driven by the pleasure of harming an animal..."
- "Primate models are only used when animals such as rats and mice cannot be used"
- "Producing a new medicine is a lengthy and complex process... Tests on animals play a vital role"
- "Research on animals has contributed to almost every medical advance of the last century."
- "Research using animals has made an important contribution to advances in medicine and surgery...
- "Research using animals is essential to produce sufficient evidence efficacy and safety before proceeding to trials involving humans"
- "Research using non-human primates has played a major role in improving human and animal health, and this continues to be the case"
- "Studies using non-human primates are undertaken alongside other animal models and observational and intervational research using humans and in vitro approaches."
- "The finding demonstrates how critically important studies in monkeys are to the understanding of HIV infection...Current proposals to restrict non-human primate research in the EU could prevent this type of work..."
- "The idea, as I understand it, is that fundamental truths are revealed in laboratory experiments on lower animals and are then applied to the problems of the sick patient... It is plain nonsense."
- "The recent discovery of highly specific antidepressants and anti-anxiety medications would not have been possible without the use of animal models"
- "The use of animals in medical research and safety testing is a vital part of the quest to improve human health."
- "the work on [polio] prevention was long delayed by... misleading experimental models of the disease in monkeys"
- "There are some answers which are very difficult to do on anything other than a primate"
- "There is no way that the heart-lung machine could have been devised and developed other than through studies on living creatures"
- "There needs to be clearer communication for the public avout how valuable it [animal testing] is.
- "until suitable alternatives are found, this vital work should continue so that hundreds of millions more lives can be saved in the future"
- "We remain of the view that in many areas of research we are still reliant on primates to achieve our goals for improving human health"
- "With primate research able to make real contibutions to alleciating devastating conditions like Parkinson's disease and HIV/AIDS, the harmful consequences that could result from abandoning this work are clear"
- "Without animal testing, there will be no new drugs for new or hard-to-treat diseases..."
- "[A primate ban] would force us to abandon research that could lead to treatments for Alzheimer's, motor neurone disease, strokes and many other illnesses"
- "[knockout mice] truly provided a revolution in mammalian biology,
- "[monkeys] are used only when no other species and no alternatice approach can provide the answers to questions about such conditions as Alzhemers, stroke, Parkinson's, spinal injury, hormone disorders, and vaccines for HIV"
- 'Although rare, the use of primates in medical research and testing is invaluable, as an essential aspect of work wihch provides the best hope for breakthroughs in important areas..."
- 'Animal tests...less predicitve than tossing a coin.'
- 'Animals are only used where deemed absolutely necessary and their use is rigorously regulated by UK legislation which is the toughest in the world. '
- 'Green Party policy is to phase out all animal testing...'
- 'I support [FRAME's] objectives, largely because I do not believe that results of tests conducted on animals will be neccessarily relevant to human beings...'
- 'I was very much afraid. Before this, we had been doing this work only on pigs.'
- 'properly controlled medical research involving animals... will prove relavent to increasing knowledge of human health in the future"
- 'The animal testing regime... is utterly futile'
- 'The use of animals in medical research remains absolutely essential....'
- 'We are concerned by the upward trend in the use of animals in scientific procedures...'
- 'We are proud of our standards, we are proud of the way we go about our experiments and the fact that the animals do not suffer in almost all situations....'
- Les enquêtes d’experts indépendants
- House of Lords Select Committee on Animals in Scientific Procedures
- Identifying the enviromental causes of disease:
- In vivo sciences in the UK: sustaining the supply of skills in the 21st century
- Investigation into the Home Office regulation of animal experimentation
- Investigations into adverse incidents during clinical trials of TGN1412
- Memorandum for House of Lords Select Committee on Animals in Scientific Procedures
- Review of cost-benefit assessment in the use of animals in research
- Study into the use of non-human primates (NHP) in research - (Weatherall report)
- The Duff Report
- The Ethics of Research Involving Animals
- The use of animals in vaccine testing for humans
- The use of genetically modified animals
- Toxicity Testing in the 21st Century: A Vision and a Strategy (Brief Summary)
- UK Stem Cell Initiative
- Critiques de livres
- Biographies
- Organisations de recherche
- 3M
- Abbott Laboratories Ltd
- Academy of Medical Royal Colleges
- Action Medical Research
- Allergan
- Alzheimer's Society
- Alzheimers Research Trust
- Amersham Place
- Amicus
- Animal Procedures Committee
- Aptuit (Edinburgh) Ltd
- Association for the Study of Animal Behaviour
- Association of Medical Research Charities
- Association of the British Pharmaceutical Industry
- Astellas Pharma
- Asthma UK
- Aston University Birmingham
- AstraZeneca
- Babraham Institute
- Baxter
- Bayer
- BioIndustry Association
- Biomedical Research Education Trust
- Biosciences Federation
- Biotechnology and Biological Sciences Council ( BBSRC)
- Boyd Group
- Breakthrough Breast Cancer
- Breast Cancer Campaign (BCC)
- Bristol-Myers Squibb
- British Association for Psychopharmacology
- British Heart Foundation
- British Medical Association
- British Neuroscience Association
- British Pharmacological Society
- British Psychological Society
- British Society for Animal Science
- British Society for Immunology
- British Veterinary Association
- Cancer Research UK
- Centre for Ecology & Hydrology
- Charles River Laboratorie
- City University
- Coalition for Medical Progress
- Council for International Organizations of Medical Sciences (CIOMS)
- Council of Heads of Medical Schools
- Covance
- De Montfort University
- Deafness Research UK (aka The Hearing Research Trust)
- DebRA UK
- Defra
- Department of Health
- Diabetes UK
- DuPont
- EFPIA (The European Federation of Pharmaceutical Industries and Associations)
- Farm Animal Welfare Council
- GE Healthcare
- Glasgow Caledonian University
- GlaxoSmithKline (GSK)
- Harlan
- Heart Research UK
- Help the Aged
- Home Office
- Huntingdon Life Sciences (HLS)
- Imperial College London
- Institute of Animal Technology
- Institute of Food Research (IFR)
- Institute of Grassland and Environmental Research (IGER)
- International Council for Laboratory Animal Science (ICLAS)
- IVTIP
- Jeans for Gens
- Johnson & Johnson
- Juvenile Diabetes Research Foundation
- Kidney Research UK
- King's College London
- Laboratory Animal Veterinary Association
- Laboratory Animals Breeders Association of Great Britain
- Laboratory Animals Science Association
- Lundbeck
- Medical Mouse
- Medical Research Council
- Meningitis Research Foundation
- Merck, Sharp and Dohme
- Migraine Trust
- Motor Neurone Disease Association
- Multiple Sclerosis Society
- Muscular Dystrophy Campaign
- National Centre for the 3Rs
- National Institute for Biological Standards and Control (NIBSC)
- National Institute for Medical Research
- National Osteoporosis Society
- Novartis
- Novo Nordisk
- Nuffield Council on Bioethics
- Open University
- Parkinson's Disease Society
- Patients' Voice for Medical Advance
- Pfizer
- Physiological Society
- Pro-Test
- Proctor & Gamble
- Queen Mary College, University of London
- Queen's University Belfast
- Reckitt Benckiser plc
- Roche
- Roslin Institute (RI)
- Royal Society
- Sanofi-Aventis
- Science Media Centre
- Sense about Science
- Sequani
- Sheffield Hallam University
- SHERT, Scottish Hospital Endowments Research Trust
- Shire plc
- Society for Endocrinology
- Society for Experimental Biology
- Society of Toxicology
- St George's Hospital Medical School
- Stand up for Science
- Syngenta
- The Academy of Medical Sciences
- The People's Petition
- The PSP Association
- The University of Birmingham
- UCL
- Understanding Animal Research
- Universities Federation for Animal Welfare
- University House
- University Loughborough
- University of Aberdeen
- University of Bath
- University of Belfast
- University of Bristol
- University of Cambridge
- University of Cardiff
- University of Derby
- University of Dundee
- University of Edinburgh
- University of Glamorgan
- University of Glasgow
- University of Leeds
- University of Leicester
- University of Liverpool
- University of Manchester
- University of Newcastle upon Tyne
- University of Oxford
- University of Roehampton
- University of Salford
- University of Sheffield
- University of Southampton
- University of St Andrews
- University of Strathclyde
- University of Wales, Aberystwyth
- University of Warwick
- University of York
- Univesity of Nottingham
- Veterinary Laboratories Agency
- Wellcome Trust
- World Medical Association
- Eli Lilly and Company
- Genzyme
- The Stroke Association
- Réglementation et Législation
- EU Directive on the protection of animals used for scientific purposes
- Animal Enterprise Protection Act
- Animal Welfare Act
- Animal Welfare Act - New Zealand
- Animal Welfare Act amendments 1970
- Animal Welfare Act amendments 1976
- Animals (Scientific Procedures) Act
- Australian code of practice for the care and use of animals for scientific purposes
- Code of Federal Regulations - Animal Welfare
- EU council directive 76/768/EEC
- EU directive 86/609/EEC
- European Chemicals Regulation (REACH) 1907/2006/EC
- Improved Standards for Laboratory Animals Act
- ETS 123
- Liens