Sequencing & analysis of the mouse genome
In 2002 the initial sequence and analysis of the mouse genome was published in Nature by the Mouse Genome Sequencing Consortium, a public-private partnership formed in 2000 to accelerate sequencing of the code. As the beginning of the 20th Century saw the birth of immunology - the key to understanding how the human body responds to pathogenic organisms, and how they can be controlled, the beginning of the 21st Century saw the first steps towards understanding the genetics of humans and other animals.
This major advance in physiology allows us to identify the functions of particular genes, and understand how they are controlled. The sequencing of the mouse genome has been hailed as providing the experimental key to the human genome, since 99% of human genes have equivalents in the mouse.
Work in mice has already greatly advanced our understanding of gene function and the genetic causes of disease. It has greatly accelerated understanding of general physiology, allowing the development of treatments for genetic disorders and improved, better targeted treatments for other illnesses.